Table 10.

Summary of D-limonene, Doxorubicin, & Temozolomide docked with Mitogen-Activated Protein Kinase 6

No.	Protein	Compound	Binding Energy (Kcal/Mol)	Inhibition constant (Ki) (mM)	No. of H-bonds	Amino Acid involved in interaction
1	Mitogen-activated protein kinase 6 (6DTL)	D-limonene	-5.59	79.87	0	Lys191(A), Tyr229(A), Arg230(A), Leu234(A), Ile245(A)
2	Mitogen-activated protein kinase 6	Doxorubicin	-5.58	81.68	8	Val270(A), Arg297(A). Tyr298(A), Leu235(A), Asn237(A), Asp268(A), His269(A)
3	Mitogen-activated protein kinase 6	Temozolomide	-4.84	282.85	8	Ser238(A), Thr242(A), Pro333(A), Arg334(A)