Table 1.
Variables | All patients (N=23,242) | Successful weaning (n=19,025) | Prolonged mechanical ventilation or mortality (n=4217) | P value |
Age (y), mean (SD) | 64.4 (15.9) | 63.7 (15.9) | 67.8 (15.8) | <.001 |
Male sex, n (%) | 14,274 (61.4) | 11,935 (62.7) | 2339 (55.5) | <.001 |
Height (cm), mean (SD) | 169.7 (10.8) | 170 (10.8) | 168.7 (10.9) | <.001 |
Weight (kg), mean (SD) | 83.3 (23.2) | 83.8 (22.7) | 81.0 (25.4) | <.001 |
Body temperature (°C), mean (SD) | 36.6 (1.3) | 36.7 (1.2) | 36.5 (1.6) | <.001 |
WBCa count (per 109/L), mean (SD) | 13.0 (7.5) | 12.7 (6.9) | 14.3 (9.8) | <.001 |
NLb ratio, mean (SD) | 9.1 (10.9) | 8.3 (9.3) | 12.3 (15.7) | <.001 |
Hemoglobin (g/dL), mean (SD) | 10.4 (2.1) | 10.4 (2.1) | 10.6 (2.4) | <.001 |
Platelet count (per 109/L), mean (SD) | 190.4 (100.9) | 188.9 (97.1) | 197.4 (116.2) | <.001 |
BUNc (mg/dL), mean (SD) | 24.4 (19.4) | 22.4 (17.2) | 33.1 (25.4) | <.001 |
Creatinine (mg/dL), mean (SD) | 1.3 (1.3) | 1.2 (1.2) | 1.7 (1.5) | <.001 |
Albumin (g/dL), mean (SD) | 3.2 (0.4) | 3.2 (0.4) | 3.1 (0.5) | <.001 |
Total bilirubin (mg/dL), mean (SD) | 1.3 (3.1) | 1.1 (2.4) | 2.2 (5.2) | <.001 |
Prothrombin time (INRd), mean (SD) | 1.5 (0.7) | 1.4 (0.6) | 1.7 (1.1) | <.001 |
pH, mean (SD) | 7.3 (0.1) | 7.4 (0.1) | 7.3 (0.1) | <.001 |
Sodium (mEq/L), mean (SD) | 138.9 (4.6) | 138.9 (4.3) | 138.9 (5.9) | .900 |
Potassium (mEq/L), mean (SD) | 4.2 (0.7) | 4.2 (0.7) | 4.3 (0.8) | <.001 |
Lactate (mmol/L), mean (SD) | 2.6 1.9) | 2.4 (1.5) | 3.7 (3.1) | <.001 |
Bicarbonate (mEq/L), mean (SD) | 23.0 (4.7) | 23.4 (4.2) | 21.1 (5.9) | <.001 |
Anion gap (mEq/L), mean (SD) | 14.4 (4.6) | 13.7 (4.0) | 17.3 (5.8) | <.001 |
SOFAe, mean (SD) | 2.9 (2.8) | 2.7 (2.5) | 3.9 (3.5) | <.001 |
SAPS IIf, mean (SD) | 40.0 (15.0) | 37.5 (13.3) | 51.6 (16.7) | <.001 |
Duration of MVg (days), mean (SD) | 2.8 (5.7) | 1.7 (2.7) | 8.1 (10.6) | <.001 |
aWBC: white blood cell.
bNL: neutrophil or lymphocyte.
cBUN: blood urea nitrogen.
dINR: international normalized ratio.
eSOFA: Sequential Organ Failure Assessment.
fSAPS II: Simplified Acute Physiology Score II.
gMV: mechanical ventilator.