. 2023 Nov 10;63(22):7239–7257. doi: 10.1021/acs.jcim.3c00950

Table 3. Performance Comparison of EvoIndMM with Different Features on the Test Set of Benchmark Data Set^a.

features	MCC	ACC	recall/sen	Spe	Pre	NPV	F₁	ER	FPR	FNR
VEP^#	0.8348	0.9175	0.9105	0.9241	0.9200	0.9150	0.9152	0.0387	0.0759	0.0895
ESM-1b^#	0.5801	0.7901	0.7633	0.8157	0.7989	0.7823	0.7807	0.0941	0.1843	0.2367
ProtT5-XL-U50^#	0.6137	0.8068	0.7772	0.8351	0.8188	0.7963	0.7975	0.0842	0.1649	0.2228
combined^#	0.8390	0.9195	0.9087	0.9299	0.9255	0.9140	0.9170	0.0358	0.0701	0.0913

Note: VEP^#, ESM-1b^#, ProtT5-XL-U50^# mean EvoIndMM only with VEP outputs, or ESM-1b embeddings, or ProtT5-XL-U50 embeddings. Combined^# represents the concatenation of VEP outputs, ESM-1b and ProtT5-XL-U50 embeddings.

Table 3. Performance Comparison of EvoIndMM with Different Features on the Test Set of Benchmark Data Seta.

Table 3. Performance Comparison of EvoIndMM with Different Features on the Test Set of Benchmark Data Set^a.