Table 3.

Sample size for prevalence outcomes

	Mali	Kenya	Zambia
Cluster per arm	38	35	35
α (2-tailed)	0.05	0.05	0.05
Power	90%	80%	90%
Baseline parasite prevalence measured by RDT among participants aged 6 months and older	50%	29.0%a	50.0%
Reduction in baseline prevalence	30%	30%	30%
ICC = intracluster correlation coefficient (coefficient of variation)	0.16 (cv = 0.4)	0.05	0.10
Non-response	20%	20%	20%
Sample size per cluster (accounting for non-response)	25 (32)	24 (30)	16 (20)
Total sample size per survey round/year (accounting for non-response)	1900 (2432)	1680 (2100)b	1120 (1400)

^aPrevalence estimates are for individuals aged ≥ 1 month (Kenya only)

^bPer year in Kenya as trial uses a continuous survey approach