Table 2.

Estimated Hazard ratios (HR) and corresponding 95% confidence intervals regarding progression-free survival in the one-stage meta-analysis

References	Estimated HR	Estimated 95% CI
CDKN2A/B deletion (homozygous or heterozygous) versus wild-type
Sievers et al. [37]	6.83	4.20–11.10
Driver et al. [6]	10.47	6.05–18.11
Wang et al. [46]	5.42	3.89–7.55
Khan et al. [16]	8.91	5.81–14.23
Entire IPD Cohort	6.83	5.50–8.47
Homozygous CDKN2A/B deletion versus wild-type
Sievers et al. [37]	6.83	4.20–11.10
Driver et al. [6]	16.18	6.10–42-96
Wang et al. [46]	6.79	4.49–10.26
Khan et al. [16]	12.32	6.25–24.31
Entire IPD Cohort	8.35	6.36–10.95
Heterozygous CDKN2A/B deletion versus wild-type
Driver et al. [6]	9.30	5.00–17.30
Wang et al. [46]	4.19	2.52–6.97
Khan et al. [16]	7.43	4.08–13.52
Entire IPD Cohort	5.52	3.99–7.62