Table 2.
Effects of lymphocyte subsets on respiratory failure in patients with acute exacerbation of COPD
| Variables | Respiratory Failure (N = 48) | No Respiratory Failure (N = 76) | P Value | ||
|---|---|---|---|---|---|
| N | Value | N | Value | ||
| T lymphocytes%a | 48 | 65.40 ± 10.86 | 76 | 67.15 ± 12.58 | 0.43 |
| CD4+ T cells%a | 48 | 37.69 ± 11.28 | 76 | 40.21 ± 10.30 | 0.20 |
| CD8+ T cells%b | 48 | 25.4(17.9,32.3) | 76 | 25.4(19.5,31.6) | 0.98 |
| CD4+CD8+ T cells%b | 48 | 0.68(0.38,1.11) | 76 | 0.89(0.62,1.54) | 0.02 |
| CD4−CD8− T cells%b | 48 | 1.68(0.66,3.75) | 76 | 1.65(0.69,3.16) | 0.82 |
| NK cells%b | 48 | 21.0(11.7,27.7) | 76 | 18.0(11.2,28.8) | 0.77 |
| T4/T8 ratio%b | 48 | 1.56(0.98,2.03) | 76 | 1.70(1.18,2.38) | 0.30 |
| B lymphocytes%b | 48 | 11.4(7.8,17.2) | 76 | 11.7(6.8,15.7) | 0.74 |
COPD chronic obstructive pulmonary disease, NK cells natural killer cells
Data are expressed as
amean ± SD
bmedian; 25–75th percentile. P values: to evaluate the differences between the two groups, an independent t-test was used to analyze the normally distributed continuous variables; the Mann–Whitney U test was used to analyze the non-normally distributed variables