Table 3.
Subgroup analysis for the effect of the TyG index and eGFR on the risk of cardiovascular diseases
| Subgroup 1 | Subgroup 2 | |||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| TyG < median & eGFR ≥ 60 | Ref | |||
| TyG < median & eGFR < 60 | 1.462 (0.783–2.648) | 0.218 | 1.484 (0.795–2.690) | 0.201 |
| TyG ≥ median & eGFR ≥ 60 | 1.183 (1.052–1.330) | 0.005 | 1.162 (1.033–1.307) | 0.013 |
| TyG ≥ median & eGFR < 60 | 1.928 (1.215–3.032) | 0.005 | 1.891 (1.191–2.976) | 0.006 |
eGFR was calculated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation; unit of eGFR: ml/minute/1.73 m2; median value of the TyG index: 8.6
Age, sex, residence, marriage, education level, BMI level, smoking status, hypertension, diabetes, and nonHDL cholesterol were adjusted
Subgroup 1: among 5436 participants without treatments for diabetes, hypertension or dyslipidemia at baseline; subgroup 2: among 3019 participants without treatments for diabetes, hypertension or dyslipidemia at baseline or during follow-up
RR risk ratio, CI confidence interval, eGFR estimated glomerular filtration rate, TyG triglyceride-glucose index, HDL high density lipoprotein