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| PI4KIIIβ pIC50a | CPE pIC50b | Δ(CPE-PI4KIIIβ) | Solubility (μg mL−1) | Chrom LogD7.4 | AMP (nm s−1) | |
| 3 | 6.3 ± 0.060 | 6.8 ± 0.063 | 0.5 | 12 | 7.2 | n.d. |
| 4 | 7.2 ± 0.101 | 8.2 ± 0.058 | 1.0 | 15 | 6.2 | 215 |
| 5 | 7.2 ± 0.145 | 7.0 ± 0.063 | −0.9 | — | — | 510 |
| 6 | 8.1 | 7.6 ± 0.005 | −0.5 | — | — | 360 |
Compound incubated with protein for 40 minutes.
Compound incubated with cells for 48 hours.
