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. 2023 Oct 17;4(12):1111–1122. doi: 10.1039/d3cb00142c

Biological data for 8 and control compounds 7 and 9.

graphic file with name d3cb00142c-u3.jpg
PI4KIIIβ pIC50a CPE pIC50b Δ(CPE-PI4KIIIβ)
7 7.4 ± 0.080 7.4 ± 0.105 0
8 6.3 ± 0.060 7.3 ± 0.085 1.0
9 6.5 6.7 ± 0.073 0.2
a

Compound incubated with protein for 40 minutes.

b

Compound incubated with cells for 48 hours.