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. 2023 Oct 17;4(12):1111–1122. doi: 10.1039/d3cb00142c

Biochemical data for 11 and control compound 10.

graphic file with name d3cb00142c-u5.jpg
PI4KIIIβ pIC50a CPE pIC50b Δ(CPE-PI4KIIIβ)
10 6.6 6.4 ± 0.017 −0.2
11 <5.0 ± 0.00 6.0 ± 0.686c >1.0
a

Compound incubated with protein for 40 minutes.

b

Compound incubated with cells for 48 hours.

c

On one test occasion was inactive (<5).