Fig. 8. Small molecule modulators of NLRP1, 3 and 6. (A) DPP8 and 9 inhibitor Val-boroPro triggers NLRP1 and CARD8 inflammasomes. (B) Representative NLRP3 inhibitors. (C) NLRP3 agonist BMS-986299. (D) NLRP6 agonist lipoteichoic acid.
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