Table 2.
Cognitive and psychological assessment
| Cognitive assessment | Cognitive functions | Measures |
| BICAMS CVLT |
Verbal episodic memory | Total free recall (/60) |
| BVMT-R | Visuospatial episodic memory | Total free recall (/12) |
| SDMT | Information processing speed | Number of correct substitutions |
| Direct and forward digit spans | Working memory | Level of the span Total number of correct responses |
| SCWT | Inhibition | Time to complete each condition Total number of errors |
| TMT | Reactive flexibility | Time to complete each condition Total number of errors |
| Verbal fluencies | Spontaneous flexibility | Number of different words. |
| TOL | Planification | Number of movements Latence and total times |
| MET | Planification | Errors and time to complete |
| D2 | Selective attention | Number of correct items in all trial Number of incorrect responses |
| PASAT | IPS / working memory | Number of correct responses (/60) |
| Psychological assessment | Psychological dimensions | |
| Subjective cognitive decline (SCD) | Cognitive complaints | 0–96, with higher score indicating more SCD. |
| BDI-FS | Depression | 0–21 |
| STAI-Y | Anxiety | 20–80 |
| VAS | Fatigue |
Other cognitive assessments complement primary cognitive measures. All additional cognitive assessment is listed in table 2. Details on description and measures of each test are reported in the additional document (online supplemental data 1).
BDI-FS, Fast-Screen Beck Depression Inventory; BICAMS, Brief International Cognitive Assessment for Multiple Sclerosis; BVMT-R, Brief Visuo-spatial Memory Test; CVLT, California Verbal Learning Test; MET, Multiple Errands Test; PASAT, Paced Auditory Serial Addition Test; SCWT, Stroop Color-Word Test; SDMT, Symbol Digit Modalities Test; STAI-Y, State Trait Anxiety Inventory; TMT, Trail Making Test; TOL, Tower of London; VAS, Visual Analog Scale.