FIG. 3.

Enantiomers, compounds 1a and 2, exhibit different activities in the gel-based assay. Compound (Cmpd) 1a was active at 10 μM, as demonstrated by the loss of fully processed nonstructural proteins NS3, NS4B, and NS5B, while its enantiomer, compound 2, was inactive at 100 μM. P, precursor proteins. MW, molecular weight marker (in thousands).