TABLE 3.
Effect of pEM-2 (d) on the lethality induced by peritoneal infection of gram-negative bacteriaa into mice
Mouse treatment group | Lethality (no. of deaths/total no. of mice)b |
---|---|
Saline control | 0/4 |
pEM-2 (D) + saline | 0/8 |
E. coli + saline | 12/12 |
E. coli + pEM-2 (d) | 9/12c |
S. enterica serovar Typhimurium + saline | 5/5 |
S. enterica serovar Typhimurium + pEM-2 (d) | 4/5c |
E. coli ATCC 25922 and S. enterica serovar Typhimurium ATCC 14028.
All deaths occurred within the first 24 h.
Nonsignificant (P > 0.05) reduction, by Fisher's exact test.