Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 1998 Jan;180(1):143–151. doi: 10.1128/jb.180.1.143-151.1998

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 1998, American Society for Microbiology

PMC Copyright notice

FIG. 3 — Comparison of the deduced amino acid sequences of the peptide synthetase modules. (A) Modules located on the 7.9-kb EcoRI fragment (SrcpsB) and the 5.3-kb ApaI fragment (SrcpsA) (Fig. 2B) are compared to peptide synthetase modules from Streptomyces fradiae A54145 (SfcpsA), N. lactamdurans (NlpcbA), Penicillium chrysogenum (PcacvA), B. subtilis (BssrfA), and Pseudomonas aeruginosa (PafpvA). The conserved motifs (A through J) (33) are shown as dashes. The consensus (Cons) line contains letters for amino acids showing 100% conservation and asterisks for conservative amino acid substitutions. (B) The segment of DNA (Srepim) from the 7.9-kb EcoRI fragment containing epimerase conserved motifs (Fig. 2B) is compared to peptide synthetase segments encoding epimerase activity from Streptomyces pristinaespiralis (Spepim), N. lactamdurans (Nlepim), B. brevis (Bbepim), B. subtilis (Bsepim), and P. crysogenum (Pcepim). The conserved motifs and consensus sequences are depicted as in panel A.

FIG. 3 — Comparison of the deduced amino acid sequences of the peptide synthetase modules. (A) Modules located on the 7.9-kb EcoRI fragment (SrcpsB) and the 5.3-kb ApaI fragment (SrcpsA) (Fig. 2B) are compared to peptide synthetase modules from Streptomyces fradiae A54145 (SfcpsA), N. lactamdurans (NlpcbA), Penicillium chrysogenum (PcacvA), B. subtilis (BssrfA), and Pseudomonas aeruginosa (PafpvA). The conserved motifs (A through J) (33) are shown as dashes. The consensus (Cons) line contains letters for amino acids showing 100% conservation and asterisks for conservative amino acid substitutions. (B) The segment of DNA (Srepim) from the 7.9-kb EcoRI fragment containing epimerase conserved motifs (Fig. 2B) is compared to peptide synthetase segments encoding epimerase activity from Streptomyces pristinaespiralis (Spepim), N. lactamdurans (Nlepim), B. brevis (Bbepim), B. subtilis (Bsepim), and P. crysogenum (Pcepim). The conserved motifs and consensus sequences are depicted as in panel A.