TABLE 4.

Relationship between mutation frequency, drug resistance phenotype, and patient history of TB for 169 genotypically distinct isoniazid-resistant isolates

Parameter	Total no. of isolates	No. of isolates with katG 315 mutationa:		P for katG 315	No. of isolates with inhA −15 mutation:		P for inhA −15
		ACC	Other		T	C
Resistance profile
Isoniazid monoresistant	85	51	33	0.82	20	65	0.88
Isoniazid and streptomycin only	41	27	14	0.42	9	32	0.90
MDR M. tuberculosis	41	21	19	0.43	8	33	0.79
Other	2	0	2		1	1
History of TB
No	89	53	36	0.33	21	68	0.39
Yes	26	11	13		4	22
Unknown	54	35	19		13	41
Total	169	99	68		38	131

^aFor two isolates, katG 315 could not be characterized; the locus could not be amplified due to a probable gene deletion.