TABLE 1.
Electrocardiographic parameters measured in the experimental groupsa
| Experimental group (no. of mice) | Heart rate (no. of beats/min) | PR interval (ms) | P-wave duration (ms) | PR segment (ms) | Intrinsicoid deflection (ms) | QT interval (ms) | QT | Cardiac conduction disturbances (no. of mice) |
|---|---|---|---|---|---|---|---|---|
| Infected (8) | 270.3 ± 30.3 | 39 ± 2.6 | 18.5 ± 2.4 | 21.9 ± 1.4 | 16.1 ± 2.9 | 41 ± 2.5 | 2.9 ± 0.2 | IVCD (5), AVB (2), ES (1) |
| Infected and treated with benznidazole (10) | 256.7 ± 15.7 | 35.5 ± 2.1b | 21.6 ± 0.9 | 13.2 ± 1.4b | 15.8 ± 1.7 | 43.5 ± 2.8 | 2.6 ± 0.2 | IT-IVCD (2) |
| Healthy (18) | 215.3 ± 18.5 | 36.5 ± 1.2 | 19.7 ± 0.7 | 16.9 ± 0.8c | 9 ± 0.7c | 32.2 ± 1.4c | 1.9 ± 0.9c | IT-IVCD (1), ASI (1) |
a
Values represent the means ± standard errors of the means for individual mice. IVCD, intraventricular conduction disturbance; AVB, atrioventricular block; ES, extrasystole; IT-IVCD, intermittent intraventricular conduction disturbance; ASI, acute subendocardial ischemia.
b
P < 0.05 compared to the results for untreated infected mice.
c
P < 0.05 compared to the results for the T. cruzi-infected groups.