TABLE 2.
Fluoroquinolone MICs for S. marcescens strainsa
| Strainb | MIC (μg ml−1)c
|
||
|---|---|---|---|
| CIP | NOR | OFX | |
| UOC-67 | 0.032 | 0.125 | 0.5 |
| T-861 | 4 | 32 | 4 |
| UOC-67WL | 32 | 64 | 32 |
| UOC-67WLN | 8 | 32 | 16 |
| UOC-67WLO | 4 | 16 | 8 |
Results represent values obtained from three independent experiments.
UOC-67 is the wild-type strain of S. marcescens, T-861 is the clinical isolate, and UOC-67WL, UOC-67WLN, and UOC-67WLO are the mutant strains generated by serial passaging of UOC-67 in the media supplemented by ciprofloxacin, norfloxacin, and ofloxacin, respectively.
CIP, ciprofloxacin; NOR, norfloxacin; OFX, ofloxacin.