TABLE 1.
Characterization of blaCTX-M-containing Salmonella isolates from humans in England and Wales
| Isolate | Serotype or phagetype | Date isolated | Resistance patterna | Ctx MIC (mg/liter) | Cazb MIC (mg/liter) | No. of CTX-M genes | Foreign travel association | Transferable |
|---|---|---|---|---|---|---|---|---|
| C1 | Anatum | Sept 01 | AmpLexRadCxmCroCtx | ≥ 128 | ≥ 256 | 15 | Pakistan | Conjugation |
| C3 | Stanley | Nov 02 | AmpLexRadCxmCroCtxChlGenNeKanStrSuSptTetNalCip | ≥ 128 | 3 | 17 or 18 | Thailand | Conjugation |
| C4 | Virchow 19 | Sept 97 | AmpLexRadCxmCroCtxNeKanStrSuSptTetTmpFu | 32 | 1 | 9 | No | Conjugation |
| C5 | Virchow 19 | Sept 97 | AmpLexRadCxmCroCtxNeKanStrSuSptTetTmpFu | 16 | 1 | 9 | No | No |
| C6 | Virchow 19 | Dec 97 | AmpLexRadCxmCroCtxNeKanStrSuSptTetTmpFu | 16 | 1 | 9 | Spain | Conjugation |
| C7 | Virchow 19 | Jul 98 | AmpLexRadCxmCroCtxNeKanStrSuSptTetTmpFu | 32 | 1 | 9 | Spain | No |
| C8 | Virchow 19 | Sept 99 | AmpLexRadCxmCroCtxStrSuSptTetTmpFuNalCip | 16 | 0.75 | 9 | Spain | Conjugation |
| C9 | Virchow 37 | Sept 01 | AmpLexRadCxmCroCtxNeKanStrSuSptTetTmpFu | 32 | 0.75 | 9 | No | No |
| C10 | Enteritidis 6a | Oct 01 | AmpLexRadCxmCroCtx | ≥ 128 | 3 | 17 or 18 | No | Conjugation |
| C11 | Virchow 31 | Nov 01 | AmpLexRadCxmCroCtxKanStrSuSptTetTmpFuNalCip | 32 | 1 | 9 | Minorca | Transformation |
| C12 | Typhimurium UNT | Jul 02 | AmpLexRadCxmCroCtx | ≥ 128 | ≥ 256 | 15 | No | Conjugation |
| C13 | Typhimurium UNT | Jul 03 | AmpLexRadCxmCroCtx | ≥ 128 | ≥ 256 | 15 | No | Conjugation |
| C15 | Enteritidis 1 | Jul 03 | AmpLexRadCxmCroCtxGenKanNalCip | ≥ 128 | ≥ 256 | 15 | No | Transformation |
| C16 | Virchow 19 | Sept 03 | AmpLexRadCxmCroCtxSuSptTmpFuNalCip | 32 | 2 | 9 | No | Conjugation |
a
Chloramphenicol (Chl), gentamicin (Gen), neomycin (Ne), kanamycin (Kan), streptomycin (Str), sulfonamide (Su), spectinomycin (Spt), tetracycline (Tet), trimethoprim (Tmp), furazolidone (Fu), nalidixic acid (Nal), ciprofloxacin (Cip). All isolates were sensitive to imipenem and cefoxitin when tested by a disk diffusion method according to NCCLS guidelines.
b
Caz, ceftazidime.