FIG. 1.

Effect of CPT on L. donovani growth. L. donovani C1 and LdRCPT.160 parasites were grown in the presence of increasing concentrations (0, 10, 25, and 50 μM) of CPT. Optical density was monitored for 6 days. Proliferation of L. donovani C1 in the absence of any treatment was considered as a maximal growth control. The parasite growth is expressed as a percentage of the optical density compared with that for the control. Results (percent over control ± standard error) are representative of three experiments performed in triplicate.