Table 1.
Sociodemographic and Clinical Characteristics of Samples 1 and 2.
| Sample 1 | Sample 2 | |||||
|---|---|---|---|---|---|---|
| SCZ (N = 66) | ASPD (N = 52) | Test Statistic/P value | ASPD (N = 26) | Controls (N = 25) | Test Statistic/P value | |
| Age mean (SD) | 32.0 (9.8) | 32.8 (12.2) | t = 0.36, P = .722 | 32.5 (8.4) | 34.6 (10.7) | t = 0.78, P = .442 |
| Sex (male) | 66 (100%) | 52 (100%) | FET, P = 1.000 | 26 (100%) | 25 (100%) | FET, P = 1.000 |
| IQ, mean (SD) | 87.8 (13.4)* | 87.7 (16.0)* | F = 0.006, P = .941 | 91.5 (9.0) | NA | |
| Time since first hospitalization in years, mean (SD) | 9.8 (8.1) | NA | NA | NA | ||
| ASPD (%) | 18 (27.3 %) | 52 (100%) | X2= 16.5, P < .001 | 26 (100%) | 0 (0%) | FET, P < .001 |
| Substance use disorder, (%) | 51 (77.3%) | 52 (100%) | Χ2 = 11.6, P < .001 | 26 (100%) | 0 (0%) | FET, P < .001 |
| Duration of substance use disorder in years, mean (SD) | 17.6 (10.4)* | 19.9 (11.9)* | t = 1.05, P = .300 | 19.0 (9.2) | NA | |
| Number of comitted homicides, median (range) | 0 (0–3) | 1 (0–3)* | FET, P = .002 | 0.5 (0–3) | NA | |
| Number of attempted homicides, median (range) | 0 (0–9)* | 0 (0–2)* | FET, P = .321 | 0 (0–1) | NA | |
| PCL-R, mean (SD) | NA | NA | 29.9 (5.2) | NA | ||
| Mean global grey matter volume, ml (SD) | 673.71 (60.8) | 687.44 (79.6) | t = 1.030, P = .306 | 633.01 (51.9) | 679.68 (65.0) | t = 2.8, P = .007 |
| Mean global white matter volume, ml (SD) | 568.71 (52.5) | 568.00 (67.7) | t = −0.063, P = .950 | 610.18 (58.1) | 630.68 (54.6) | t = 1.3, P = .200 |
*Missing values.
FET, fisher exact test; NA, Not available.