Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flowcharts for RWE studies (A) and interventional studies (B). aOthers indicates records that were not classified into key categories. bTwo lead publications did not report all information reported within the analyses and were each manually supplemented with data from an additional publication from the same cohort. Abbreviations: 3TC, lamivudine; ACHA, Asian Conference on Hepatitis and AIDS; ASHM, Australasian HIV & AIDS Conference; ASICON, National Conference of AIDS Society of India; BASHH, British Association for Sexual Health and HIV; BHIVA, British HIV Association; CAHR, Canadian Conference on HIV/AIDS Research; CROI, Conference on Retroviruses and Opportunistic Infections; DTG, dolutegravir; GeSIDA, Grupo de Estudio del SIDA-SEIMC; HIV/HEP, HIV & Hepatitis in the Americas; HIV-NAT, The HIV Netherlands Australia Thailand Research Collaboration; IAS/IAC, International AIDS Society/International AIDS Conference; ICAR, International Conference on Antiviral Research; ICASA, International Conference on AIDS and STIs in Africa; ICID, International Congress on Infectious Diseases; JSAR, Japanese Society for AIDS Research; KAP, Kenya Association of Physicians; PWH, people with human immunodeficiency virus type 1; RWE, real-world evidence; SFLS, Société Française de Lutte contre le Sida; STI, sexually transmitted infection.