Table 2.

Univariable and Multivariable (Model 0) Analysis Evaluating the Association of Baseline Clinical and Demographic Characteristics With Long COVID at Week 24 (Presence of Overall Coronavirus Disease 2019 Symptoms at Week 24 by Global Assessment)

Variable	Univariable Model				Multivariable Model (Base Model)a
	Risk Ratio	(95% CI)	P Value	Global P Valueb	Adjusted Risk Ratio	(95% CI)	P Value	Global P Valueb
Age (per 10 y) at day 0	1.00	(.89–1.12)	.96		0.99	(.87–1.14)	.93
BMI (kg/m2) at day 0
25–29.9 vs <25 [ref]	0.76	(.43–1.36)	.36	.04	0.90	(.49–1.63)	.72	.11
30–34.9 vs <25 [ref]	1.42	(.81–2.47)	.22		1.65	(.93–2.93)	.09
≥35 vs < 25 [ref]	1.51	(.85–2.67)	.16		1.40	(.75–2.64)	.29
Cigarette smoking status at day 0
Current vs never [ref]	2.39	(1.41–4.06)	.001	.10	2.41	(1.34–4.32)	.003	.07
Former vs never [ref]	1.04	(.63–1.74)	.87		0.85	(.49–1.47)	.56
Ethnicity
Hispanic or Latino vs not [ref]	0.49	(.31–.78)	.003		0.52	(.32–.84)	.007
High-risk comorbiditiesc
At least 1 vs non/not reported [ref]	1.31	(.90–1.93)	.16		1.15	(.72–1.84)	.56
Race
Black or African American vs White [ref]	1.15	(.51–2.57)	.74	.71	1.14	(.52–2.50)	.75	.85
Other vs White [ref]	0.73	(.29–1.87)	.52		0.81	(.31–2.12)	.67
Sex
Female vs male [ref]	1.81	(1.22–2.69)	.003		1.91	(1.28–2.85)	.001
Total symptom score at day 0 (per unit higher)	1.03	(1.00–1.06)	.09		1.01	(.98–1.05)	.41

Abbreviations: BMI, body mass index; CI, confidence interval; Non, none; ref=reference.

Multivariable model includes all variables together in 1 model.

Global P values provided for categorical variables with >2 categories.

High-risk comorbidities include active cancer, moderate to severe asthma, chronic kidney disease, chronic liver disease, history of cirrhosis, chronic lung disease, current smoker, cardiovascular disease, diabetes, hypertension, treatment with biologics/immunomodulators/cancer chemotherapy within 90 days of entry, human immunodeficiency virus with CD4 count <200 cells/μL, receiving corticosteroids within 30 days of entry, and obesity.