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. 2023 Nov 22;623(7989):1017–1025. doi: 10.1038/s41586-023-06639-8

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© The Author(s) 2023, corrected publication 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 4 — a, Representative micrograph (5,450 total), b, representative 2D classes, and c, density map for the CD4-B41 HT2 complex. d, Fourier shell correlation (FSC) plot of the final reconstruction for CD4-B41 HT2. e,f, Top-down (panel e) and side (panel f) views of class I CD4-BG505 HT2 model fit into class I CD4-BG505 HT2 (left) or CD4-B41 HT2 (middle) density maps and alignment of both density maps (right).