Table 3.

IC₅₀ values of 5, 11, and 12 on nitric oxide production inhibitory activities induced by lipopolysaccharide in microglial BV-2 cells

compound	IC50 (µM) a,b
5	0.7 ± 0.1***
11	1.2 ± 0.1**
12	1.6 ± 0.2**
Curcumin c	2.7 ± 0.3

**p < 0.01

***p < 0.001

^aIC₅₀ = concentration that reduces NO production by 50%

^bAsterisks denote significance compared to curcumin (positive control) according to the two-tailed t-test

^cPositive control used in this study