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. 2023 Nov 29;13:21030. doi: 10.1038/s41598-023-48508-4

Table 1.

Demographic characteristics and clinical presentation of individuals according to ZIKV infection, Thailand (2020–2023) (N = 751).

Variable All patients ZIKV positive ZIKV negative OR (95% Cl) p-value
Sex‒no./total no. (%)
Female 401/751 (53.4) 51/90 (56.7) 350/661 (53.0) Reference 0.507
Male 350/751 (46.6) 39/90 (43.3) 311/661 (47.0) 0.86 (0.55‒1.34)
Age (years)
Median (interquartile range) 35 (26‒47) 37 (29‒46) 34 (25–47)
Range 1‒92 1‒71 1‒92
Age distribution (no. [%])
≤ 15 years 83 (11.1) 9 (10.0) 74 (11.2) 1.28 (0.49‒3.40) 0.187
16–25 years 104 (13.8) 9 (10.0) 95 (14.4) Reference
26–35 years 198 (26.4) 20 (22.2) 178 (26.9) 1.19 (0.52‒2.71)
36–45 years 164 (21.8) 29 (32.2) 135 (20.4) 2.27 (1.03‒5.01)
46–55 years 91 (12.1) 12 (13.3) 79 (12.0) 1.60 (0.64‒4.00)
≥ 56 years 111 (14.8) 11 (12.2) 100 (15.1) 1.16 (0.46‒2.93)
Days from illness onset to diagnosis
Median (interquartile range) 4 (2–5) 3.5 (3–5) 3 (2–5)
Symptoms—no./total no. (%)
Fever 428/484 (88.4) 42/59 (71.2) 386/425 (90.8) 0.25 (0.13‒0.48) < 0.001
Arthralgia 164/484 (33.9) 32/59 (54.2) 132/425 (31.1) 2.63 (1.52‒4.57) < 0.001
Conjunctivitis 23/484 (4.8) 13/59 (22.0) 10/425 (2.4) 11.73 (4.87‒28.24) < 0.001
Rash 133/484 (27.5) 49/59 (83.1) 84/425 (19.8) 19.89 (9.68‒40.90) < 0.001
Myalgia 213/484 (44.0) 23/59 (39.0) 190/425 (44.7) 0.79 (0.45‒1.38) 0.407
Vomiting 71/484 (14.7) 3/59 (5.1) 68/425 (16.0) 0.28 (0.09‒0.93) 0.026
Diarrhea 33/484 (6.8) 2/59 (3.4) 31/425 (7.3) 0.45 (0.10‒1.91) 0.265
Headache 211/484 (43.6) 14/59 (23.7) 197/425 (46.4) 0.36 (0.19‒0.68) 0.001
Fatigue 132/484 (27.3) 14/59 (23.7) 118/425 (27.8) 0.81 (0.43‒1.53) 0.514
Sore throat 39/484 (8.1) 8/59 (13.6) 31/425 (7.3) 2.00 (0.87‒4.57) 0.098
Informed 484 59 425
No informed 267 31 236