Table 2.
Gene expression in 8 novel immune-network genes associate with survival.
| Gene | Coefficient | 95%–105% Range | Q-value | Gene description | Number of ImmunoSigDB gene sets |
|---|---|---|---|---|---|
| BUB1 | 1.36 ± 0.05 | 1.22–1.51 | 1.71e-8 | BUB1 mitotic checkpoint serine/threonine kinase | 5 |
| MCM6 | 1.45 ± 0.07 | 1.27–1.66 | 6.19e-8 | Minichromosome maintenance complex component 6 | 4 |
| NOSTRIN | 1.58 ± 0.11 | 1.27–1.98 | 4.49e-5 | Nitric oxide synthase trafficking | 1 |
| PAM | 0.72 ± 0.08 | 0.62–0.83 | 1.34e-5 | Peptidylglycine alpha-amidating monooxygenase | 7 |
| RNF115 | 1.42 ± 0.11 | 1.14–1.77 | 1.72e-3 | Ring finger protein 115 | 6 |
| SNCAIP | 1.40 ± 0.09 | 1.17–1.67 | 2.03e-4 | Synuclein alpha interacting protein | 1 |
| SPRR2A | 1.34 ± 0.05 | 1.22–1.46 | 1.43e-10 | Small proline rich protein 2 A | 3 |
| WEE1 | 1.32 ± 0.04 | 1.23–1.41 | 6.19e-15 | WEE1 G2 checkpoint kinase | 9 |
Coefficients <1 indicate a protective effect—associated with longer PFS. Coefficients >1 indicate a detrimental effect—associated with a shorter PFS.