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. 2023 Nov 29;14:7825. doi: 10.1038/s41467-023-43381-1

Fig. 1. The tumour-microenvironment and peripheral immune system of advanced HCC.

Fig. 1

a. Study design, patient and sample overview. b. UMAP depicting cell types identified in pre-treatment TME of advanced HCC (n = 38 tumour biopsies). c. UMAP representation of cell types identified in blood  (n = 72 PBMC samples). (cDC, conventional dendritic cells; pDC, plasmacytoid dendritic cells; DN T cells, Double negative T cells; GD T cells, Gamma-delta T cells; HCC, hepatocellular carcinoma; PD1, Programmed cell death protein 1; PDL1, Programmed death-ligand 1; scRNAseq, single-cell RNA sequencing; scTCRseq, single-cell T cell receptor sequencing; TME, tumour-microenvironment; UMAP, Uniform Manifold Approximation and Projection).