Table 1.
Demographic and clinical characteristics.
| Variables | Total (n = 315) | No recurrence (n = 137) | Recurrence (n = 178) | P value |
|---|---|---|---|---|
| Gender, n (%) | 0.127 | |||
| male | 288 (91) | 121 (88) | 167 (94) | |
| female | 27 (9) | 16 (12) | 11 (6) | |
| Tumor size n (%) | <0.001 | |||
| ≤3 cm | 85 (27) | 52 (38) | 33 (19) | |
| ＞3 cm | 230 (73) | 85 (62) | 145 (81) | |
| Tumor number, n (%) | <0.001 | |||
| 1 | 229 (73) | 115 (84) | 114 (64) | |
| ＞1 | 86 (27) | 22 (16) | 64 (36) | |
| Vascular invasion, n (%) | 0.133 | |||
| No | 198 (63) | 93 (68) | 105 (59) | |
| Yes | 117 (37) | 44 (32) | 73 (41) | |
| BCLC, n (%) | <0.001 | |||
| 0 | 55 (17) | 38 (28) | 17 (10) | |
| 1 | 115 (37) | 48 (35) | 67 (38) | |
| 2 | 34 (11) | 10 (7) | 24 (13) | |
| 3 | 111 (35) | 41 (30) | 70 (39) | |
| AFP, n (%) | 0.195 | |||
| ≤400 | 219 (70) | 101 (74) | 118 (66) | |
| ＞400 | 96 (30) | 36 (26) | 60 (34) | |
| HBV DNA, n (%) | 0.005 | |||
| ≤1000 | 97 (31) | 54 (39) | 43 (24) | |
| ＞1000 | 218 (69) | 83 (61) | 135 (76) | |
| Differentiation, n (%) | 0.907 | |||
| poor | 39 (12) | 18 (13) | 21 (12) | |
| moderate | 236 (75) | 101 (74) | 135 (76) | |
| well | 40 (13) | 18 (13) | 22 (12) | |
| Age, Mean ± SD | 50.09 ± 11.45 | 50.35 ± 11.72 | 49.88 ± 11.27 | 0.721 |
| Plt, Median (Q1,Q3) | 171 (128, 216.5) | 172 (123, 209) | 169.5 (130, 222.5) | 0.711 |
| N, Median (Q1,Q3) | 3.25 (2.46, 4.28) | 3.12 (2.41, 3.98) | 3.37 (2.49, 4.69) | 0.087 |
| L, Median (Q1,Q3) | 1.62 (1.25, 2.08) | 1.64 (1.3, 2.03) | 1.61 (1.22, 2.1) | 0.662 |
| M, Median (Q1,Q3) | 0.42 (0.32, 0.56) | 0.38 (0.3, 0.52) | 0.44 (0.33, 0.6) | 0.011 |
| NLR, Median (Q1,Q3) | 1.94 (1.54, 2.69) | 1.91 (1.52, 2.55) | 1.98 (1.58, 3.01) | 0.205 |
| TB, Median (Q1,Q3) | 14.1 (10.45, 18.1) | 14.2 (10.6, 18.7) | 14.05 (10.4, 17.95) | 0.766 |
| Albumin, Mean ± SD | 40.09 ± 4.24 | 40.47 ± 4.48 | 39.79 ± 4.04 | 0.16 |
| ALT, Median (Q1,Q3) | 38 (28, 52) | 36 (24, 48) | 40 (30, 56.75) | 0.042 |
| AST, Median (Q1,Q3) | 38 (29, 50) | 34 (27.5, 47.5) | 40 (30, 50.75) | 0.041 |
| Total cholesterol, Median (Q1,Q3) | 4.45 (3.76, 5.26) | 4.44 (3.72, 5.18) | 4.49 (3.8, 5.32) | 0.379 |
| GGT, Median (Q1,Q3) | 61 (38, 107) | 57 (32, 85.5) | 65 (42.25, 118.5) | 0.004 |
| Fibrinogen, Median (Q1,Q3) | 2.98 (2.47, 3.65) | 2.88 (2.39, 3.37) | 3.12 (2.54, 3.89) | 0.031 |
Abbreviation: Plt: platelet; N: neutrophils; L: lymphocyte; M: macrophages; NLR: neutrophils to lymphocytes ratio; TB: total bilirubin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: γ-glutamyl transpeptidase; BCLC: Barcelona Clinic Liver Cancer staging classification.