Table 2.

Univariate and multivariate logistic regression.

Characteristics	Category	Univariate analysis		Multivarite analysis
		OR (95 % CI)	P value	OR (95 % CI)	P value
Gender	male	Ref	Ref	Ref	Ref
	female	0.498 (0.223–1.111)	0.089	0.894 (0.3–2.66)	0.84
Tumor size	≤3 cm	Ref	Ref	Ref	Ref
	＞3 cm	2.688 (1.611–4.485)	<0.001	1.417 (0.488–4.111)	0.521
Tumor number	1	Ref	Ref	Ref	Ref
	＞1	2.935 (1.694–5.083)	<0.001	4.723 (1.924–11.598)	0.001
Vascular invasion	No	Ref	Ref	Ref	Ref
	Yes	1.469 (0.921–2.343)	0.106	\	\
BCLC	0	Ref	Ref	Ref	Ref
	1	3.12 (1.578–6.168)	0.001	1.841 (0.497–6.822)	0.361
	2	5.365 (2.109–13.644)	<0.001	0.721 (0.124–4.18)	0.715
	3	3.816 (1.915–7.606)	<0.001	1.34 (0.335–5.367)	0.679
AFP	≤400	Ref	Ref	Ref	Ref
	＞400	1.427 (0.873–2.332)	0.156	\	\
HBV DNA	≤1000	Ref	Ref	Ref	Ref
	＞1000	2.043 (1.258–3.318)	0.004	1.747 (0.861–3.547)	0.123
Differentiation	poor	Ref	Ref	Ref	Ref
	moderate	1.146 (0.58–2.262)	0.695	\	\
	well	1.048 (0.432–2.54)	0.918	\	\
N	\	1.178 (1.012–1.37)	0.034	0.931 (0.684–1.266)	0.647
M	\	4.84 (1.472–15.909)	0.009	2.367 (0.461–12.151)	0.302
Fibrinogen	\	1.34 (1.027–1.749)	0.031	1.178 (0.855–1.623)	0.317
Age	\	0.996 (0.977–1.016)	0.719	\	\
Plt	\	1.001 (0.998–1.004)	0.663	\	\
L	\	0.946 (0.674–1.327)	0.746	\	\
Albumin	\	0.962 (0.912–1.015)	0.155	\	\
NLR	\	1.185 (1–1.405)	0.05	1.219 (0.909–1.633)	0.185
AST	\	1.01 (0.998–1.023)	0.1	\	\
TB	\	0.994 (0.979–1.009)	0.403	\	\
GGT	\	1.003 (0.999–1.006)	0.118	\	\
ALT	\	1.004 (0.995–1.012)	0.375	\	\
Total cholesterol	\	1.098 (0.876–1.375)	0.417	\	\

Abbreviation: Plt: platelet; N: neutral granulocyte; L: lymphocyte; M: macrophages; NLR: neutrophils to lymphocyte ratio; TB: total bilirubin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: γ-glutamyl transpeptidase; BCLC: Barcelona Clinic Liver Cancer staging classification.