Table 3.
V1/2 (mV) values for WT and mutant channels and the corresponding p values by Student’s t test
| Channel | V1/2 (mV) | p Value |
|---|---|---|
| WT | −15.3 ± 0.7 (5) | |
| ΔPAS | −16.3 ± 0.8 (5) | 0.3744 |
| Y71G | −16.7 ± 0.7 (5) | 0.1950 |
| Y71F | −21.1 ± 1.0 (6)a | 0.0014 |
| Y71V | −21.4 ± 0.5 (6)a | 0.0001 |
| Y71E | −19.9 ± 0.5 (5)a | 0.0007 |
| Y71R | −17.1 ± 0.6 (5) | 0.0867 |
| D39G | −18.8 ± 0.7 (6)a | 0.0067 |
| V80G | −14.8 ± 1.1 (6) | 0.7237 |
| V83G | −15.6 ± 0.6 (6) | 0.7508 |
| R84G | −17.0 ± 0.9 (6) | 0.1831 |
| F87G | −5.6 ± 0.6 (5)a | 0.0001 |
| F130G | −12.7 ± 0.6 (6)a | 0.0195 |
| D39G/R84G | −16.8 ± 1.2 (6) | 0.3340 |
p < 0.05 by Student’s t test. p < 0.05 was considered statistically significant. p-values represent significance of Student’s t tests used to compare the V1/2 values for WT and indicated mutant channels. The number of averaged recordings from different oocytes is indicated in parentheses.