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. 2023 Nov 29;14:7857. doi: 10.1038/s41467-023-43715-z

Table 2.

Disease/outcome agnostic prediction: AUROC scores on different pretraining objectives for the 10 common and 10 uncommon diseases in Table 1

Models BERT TransformEHR
Chronic PTSD R 81.04 ±0.11 83.73 ±0.07
0 76.74 ±0.17 77.95 ±0.12
Type 2 diabetes R 85.00 ±0.10 85.72 ±0.07
0 79.97 ±0.04 81.84 ±0.05
Hyperlipidemia R 86.78 ±0.03 88.04 ±0.05
0 81.28 ±0.08 83.42 ±0.08
Loin pain R 81.47 ±0.04 88.24 ±0.05
0 76.88 ±0.12 85.37 ±0.08
Low back pain R 85.43 ±0.07 86.94 ±0.03
0 80.16 ±0.07 82.30 ±0.10
Obstructive sleep apnea R 80.74 ±0.17 82.25 ±0.16
0 73.06 ±0.08 74.69 ±0.19
Depression R 86.73 ±0.05 87.66 ±0.12
0 82.60 ±0.12 83.85 ±0.11
Obstructive airway disease R 83.57 ±0.14 86.19 ±0.07
0 76.99 ±0.08 80.27 ±0.07
Gastroesophageal reflux R 84.98 ±0.28 91.07 ±0.11
0 76.29 ±0.36 83.41 ±0.33
Arteriosclerosis R 82.21 ±0.06 88.79 ±0.10
0 75.78 ±0.08 80.03 ±0.20
Uncommon disease/outcome 0 75.63 ±0.12 80.11 ±0.12

Many common diseases are chronic in nature. We therefore study whether prior history of the same disease has an impact on prediction performance, where R is recurrent and 0 is new disease onset. ± represents standard deviation.