Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Nov 29;14:7856. doi: 10.1038/s41467-023-43364-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 9 — A Number of differentially expressed proteins. B PCA reveals evident separation based on differentially expressed proteins between the two groups. n = 5 rats/group. C Volcano plot shows the differentially expressed proteins of interests. D Upregulated pathways in the biological process enrichment analysis. Arrows: upregulated pathways of interests regarding extracellular matrix deposition and vessel regeneration. E Downregulated pathways in the biological process enrichment analysis. Arrows: downregulated pathways of interests regarding inflammatory response. F Protein-protein interaction and protein-biological process relation network analysis indicates that different biological processes during wound healing including inflammatory response, angiogenesis, and cell-matrix adhesion are interrelated based on some common differentially expressed proteins. G Heatmap shows the differentially expressed mitochondrial proteins of interests. Arrows: representative proteins related to mitochondrial oxidative stress damage. H Protein-protein interaction and protein-biological process relation network analysis reveals the key differentially expressed mitochondrial proteins involved in the oxidation-reduction process. The p values in the figure (C) and figures (D and E) are determined by two-sided unpaired t test and Fisher’s exact test, respectively.