TABLE 6.

Effect of therapeutic treatment with methylprednisolone on the macroscopic scores of colitis severity.

Parameter (%)	Edema	Erythema	Diarrhea	Blood in stool	Anorectal bleeding	Adhesion
UT	0	0	0	0	0	0
Vehicle	100 *	100 *	100 *	40 *	100 *	100 *
Mino 10 mg/kg	100 *	0 #	0 #	0 #	0 #	40 *#
Bud 0.5 µg/kg	40 *#	0 #	0 #	0 #	0 #	20 *#
Mino + Bud 5 mg/kg	0 #$	0 #	0 #	0 #	0 #	0 #$

Colitis severity was assessed in UT mice and mice treated with DSS for 4 days, followed by 3 days of daily i. p administration of methylprednisolone or vehicle (PBS) (without DSS treatment) (n = 4 per group). * denotes a significant difference from UT mice; # denotes a significant difference from DSS/vehicle-treated mice.