TABLE 3.

RR and 95% CI for radiographic incidence/progression of OA in knees included in each analysis.

	Worsening ROA (%)	Unadjusted RR (95% CI)	Adjusted RR (95% CI)
Primary analysis (n = 8127 knees)
≤4 h/day sitting n = 5464 knees	9.1%	1.0 (REF)	1.0 (REF)
>4 h/day sitting n = 2663 knees	11.3%	1.24 (1.07–1.44)	1.25 (1.08–1.50)
Stratified analysis (n = 5777 knees) Frequent worktime sitting (n = 1655 knees)
≤4 h/day sitting n = 972 knees	7.1%	1.0 (REF)	1.0 (REF)
>4 h/day sitting n = 683 knees	11.0%	1.55 (1.10–2.18)	1.60 (1.19–2.33)
Infrequent worktime sitting (n = 4122 knees)
≤4 h/day sitting n = 2939 knees	9.7%	1.0 (REF)	1.0 (REF)
>4 h/day sitting n = 1183 knees	11.4%	1.17 (0.95–1.45)	1.11 (0.89–1.39)

Note: Risk ratios in bold indicate p < 0.05. Adjusted RR were adjusted for age, BMI, sex, self-reported leisure-time walking, and baseline KL grade.

Abbreviations: 95% CI, 95% confidence intervals; OA, osteoarthritis; ROA, radiographic osteoarthritis; RR, risk ratios.