Bias	Author's judgment	Support for judgment
Risk of bias arising from the randomization process	Some concerns	Randomized allocation but no information on allocation concealment. There was no significant differences at baseline.
Risk of bias due to deviations from the intended interventions (effect of assignment to intervention)	Some concerns	Single bind study with appropriate analysis used to estimate the effect of assignment to intervention.
Risk of bias due to deviations from the intended interventions (effect of adhering to intervention)	Low risk	Participants might have been aware of the study while personnel were blinded.
Missing outcome data	Low risk	Over 95% of participants were included in analysis.
Risk of bias in measurement of the outcome	Low risk	Outcomes were measured appropriately.
Risk of bias in selection of the reported result	Low risk	All outcomes reported appropriately.