Table 2.

177Lu-PSMA-I&T.

177Lu-PSMA-I&T	Information
	Isotope 177Lu connected with PSMA-I&T, used for imaging and therapy in PC treatment.
Treatment Effects
PSA Concentration
Decrease	- 30% decrease in PSA observed in 56% of cases [Heck et al.]
	- 50% decrease in PSA observed in 58.9% of cases [Baum et al.]
Survival Parameters	- PFS: 4.1 months, OS: 12.9 months [Heck et al.]
	- PFS: 8.8 months (chemotherapy-naive), OS: 27.1 months [Barber et al.]
	- PFS: 6.0 months (post-chemotherapy), OS: 10.7 months [Barber et al.]
Toxicity
Hematotoxicity	- 9% level 3+ anemia, 6% level 3+ neutropenia, 4% level 3+ thrombocytopenia [Heck et al.]
Organ Toxicity	- Highest toxicity in parotid glands and kidneys [Heck et al.]