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. 2023 Nov 16;14:1223746. doi: 10.3389/fphar.2023.1223746

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Copyright © 2023 Wu, Liu, Ye, Hu, Ma and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LSEQ scores of dexmedetomidine (DEX) and placebo groups. The LSEQ scores for “getting to sleep” (GTS) and “quality of sleep” (QOS) were significantly increased in the DEX group compared to baseline, while the scores consistently remained lower than baseline in the placebo group. In terms of “awakening from sleep” (AFS) and “behavior following wakefulness” (BFW), the placebo group scores were lower than those of the DEX group. The subjective improvements in sleep quality resulting from DEX treatment were reflected in easier sleep onset and better overall sleep quality.