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. 2023 Oct 12;45(6):645–661. doi: 10.1093/ejo/cjad047

Table 1.

Characteristics of included studies.

No. Study Study design Participants and setting Interventions Outcome Follow-up
Period
1. Artun et al. 1997 Prospective study n = 49
University of Washington, USA
(i) Thick plain wire; 0.032 inch; mandible: only canines; n = 11
(ii) Thick spiral wire; 0.032 inch; mandible: only canines; n = 13
(iii) Thin, flexible spiral wire; 0.0205 inch; mandible: all 6; n = 11
(iv) Removable retainers; n = 14
Retainer failure 3 years
2. Bazargani 2012 RCT n = 52 (26 M, 26 F)
Mean age 18.3 ± 1.3 years
Orebro County Council, Sweden.
(i) Resin, optibond FL; n = 26
(ii) Non-resin tetric evoflow; n = 26
Mandibular canine to canine
Wire: 0 0.0195 inch multi-stranded penta-one wire
Failure rate, incidence of retainer loss or breakage failure rate 2 years
3. Taner 2012 RCT n = 66 (52 F, 14 M)
Mean age:
15.96 ± 3.21 in the direct group
19.44 ± 6.79 in the indirect groups
University of Hacettepe, Turkey
(i) Eight-braided flattened stainless steel; 0.022 inch −0.016 inch; mandible: all 6; direct bonding; n = 32
(2) Eight-braided flattened stainless steel; 0.022 inch −0.016 inch; mandible: all 6; indirect bonding; n = 34
Composite: phase II (CC)
Failures of retainers as a result of debonding, fracture, debonding and fracture, or retainer loss 6 months
4. Bolla et al. 2012 RCT n = 85 (29 male, 56 female)
Mean age: male 23.7 years, female 21.9 years
(i) Glass fibre reinforced; maxilla: all incisors (n = 14); mandible: all 6 (n = 34)
(ii) Multi-stranded wire, 0.0175 inch; maxilla: all incisors (n = 18); mandible: all 6 (n = 32)
Composite: ENA bond LC primer and flowable composite (LC)
The total number of detachments or bond failure and breakages 6 years
5. Lee 2009 Prospective study n = 300
Mean age: 15.6 ± 2.7 years
Private practice, Canada.
(i) Multi-stranded stainless steel; 0.0175 inch; straight wire; maxilla and mandible: all incisors or all 6; n = 153
(ii) Black Australian stainless steel; 0.016 inch; V-loop design; maxilla and mandible: all incisors or all 6; n = 147
Composite: Transbond LR (LC)
Wire fractures, detachment rate due to bond failure 6 months
6. Forde et al. 2018 RCT n = 60
(15 F and 15 M with median age 16 in BR)
(12 M and 18 F with median age of 17 in VFR)
St Luke’s Hospital, York
Hospital, and Leeds Dental Institute; UK.
(i) BR (0.195 in three-stranded twist flex SS wire); n = 30
(ii) VFR; n = 30
Composite: Trasbond XT
Retainer survival 1 year
7. Gunay 2018 RCT n = 120
Mean age 15.7 years (17 M and 43 F) in extraction group
Mean age of 16.2 years (20 M and 40 F) in non-extraction group
Ondokuz Mayıs University, Turkey
(i) Extraction and 0.0175 in 60 stranded SS (n = 60)
(ii) Non-extraction and 0.0195 in dead soft coaxial wire (n = 60)
Composite: Trasbond XT
Failure rate 1 year
8. Ardeshna 2011 Prospective study n = 51
University of Connecticut, USA
(i) Maxilla: fibre-reinforced thermoplastic—FRP formula A; 0.53 mm; n = 1
(ii) FRP formula A; 1.02 mm; n = 1
(iii) FRP formula B; 0.53 mm; n = 6
(iv) FRP formula B; 1.02 mm; n = 8
(v) Mandible: fibre-reinforced thermoplastic—FRP formula A; 0.53 mm; n = 15
(vi) FRP formula A; 1.02 mm; n = 6
(vii) FRP formula B; 0.53 mm; n = 10
(viii) FRP formula B; 1.02 mm; n = 29
Retainer failure 24 months
9. Zachrisson 1977 Prospective study n = 43
Age: 14–17 years
University of Oslo, Norway
(i) Heat-treated and polished blue Elgiloy; 0.036 inch or 0.032 inch; mandible: only canines; held with finger during placement; n = 22
(ii) Heat-treated and polished blue Elgiloy; 0.036 inch or 0.032 inch; mandible: only canines; ligated during placement; n = 21
Composite: Concise (CC)
Retainer loosening 12 months
10. Salehi et al. 2013 RCT n = 142 (59 male, 83 female)
Age: 14–28 years
(i) Polyethylene woven ribbon; maxilla and mandible: all 6; n = 68
(ii) Flexible spiral wire; 0.0175 inch; maxilla and mandible: all 6; n = 74
Composite: Fluoro Bond (sealant) and Heliosit Orthodontic (LC)
Bond failure 18 months
11. Talic 2016 Prospective study n = 100 (37 F and 13 M in first group; 30 F and 20 M in second group)
Mean age 21.4 ± 5.3 years for first group
Mean age 20.48 years for second group
King Saud University, Kingdom of Saudi Arabia
(i) Fixed canine to canine retainers with a light-cured nano-hybrid composite based on nano-optimized technology (Tetric-N-Flow, Ivoclar Vivadent, Schaan, Liechtenstein)
(ii) Fixed canine-to-canine mandibular and maxillary lingual retainers that were bonded with a light-cured LV composite (Transbond Supreme LV, 3M Unitek, Monrovia, California, USA)
Failure rate 6 months
12. Tacken et al. 2010 RCT n = 184 patients (90 M, 94 F; 169 analysed)
Mean age: 14 years
University of Brussels, Belgium
(i) Glass fibre reinforced (GFR500) maxilla: lateral incisor to lateral incisor (n = 45); mandible: all 6 (n = 45)
(ii) Glass fibre reinforced (GFR1000); maxilla: lateral incisor to lateral incisor (n = 48); mandible: all 6 (n = 48)
(iii) Six-stranded coaxial wire, 0.0215 inch; maxilla: lateral incisor to lateral incisor (n = 91); mandible: all 6 (n = 91)
Composite: Excite and Tetric Flow (LC)
Bond failure
Retainer failure
24 months
13. Egli et al. 2017 RCT n = 64
Mean age 19.8 years in direct, 17.2 in indirect
61% F and 39% F in direct group
50% M and 50% F in indirect
University of Geneva, Switzerland.
(i) Direct bonding; n = 30
(ii) Indirect bonding; n = 30
Composite: direct bonding—Trasbond LR (LC), Indirect—maximum cure A and B (CC)
Wire: Multi-stranded SS wire 0.0215 inch
Mandibular laterals to laterals or canine to canine
Failure rate 2 years
14. Bovali 2014 RCT n = 60 patients
Mean age:
19.8 years (direct bonding), 17.2 years (Indirect bonding)
University of Geneva, Switzerland.
(i) Multi-stranded steel wire 0.0215 inch; mandible: all 6; n = 29; direct bonding
(ii) Multi-stranded steel wire 0.0215 inch; mandible: all 6; n = 31; indirect bonding
Composite:
direct bonding, Transbond LR (LC); indirect bonding, Maximum Cure A and B (CC)
Retainer failure 6 months
15. Tang et al. 2013 RCT n = 45
22 retainers in 18 patients
31 retainers in 27 patients
Karolinska Institute and Uppsala County Council, Sweden
(i) Transbond LR composite paste with liquid resin; n = 20
(ii) Liquid resin excluded; n = 20
Wire: 0.0215-inch multi-stranded wire
Maxilla: all incisors; mandible: all 6
Failure rate 5 years
16. Pandis et al. 2013 RCT n = 220
(Median age, 16 years; interquartile range, 2 years; range, 12–47 years)
Private practice, Greece.
(i) Tru-Chrome multi-stranded wire; 0.022 inch; mandible: all 6; n = 110; Reliance (CC)
(ii) Tru-Chrome multi-stranded wire; 0.022 inch; mandible: all 6; n = 110; Flow Tain (LC) Composite: Reliance (CC) and Flow Tain (LC)
Bond failure 3.64 years
17. Rose et al. 2002 RCT 20 patients (8 F, 12 M)
Mean age 22.4 years
Freiburg University, Germany
(i) Polyethylene woven ribbon; mandible: all 6; n = 10
(ii) Multi-stranded steel wire; 0.0175 inch; mandible: all 6; n = 10
Composite: Heliosit Orthodontic (LC)
Resin fracture or Retainer loosening 2years
18. Arash et al. 2020 RCT n = 260 (44 M and 68 F)
Age: 13–30 years (20 ± 4.35 years)
Babol University of Medical Sciences, Islamic Republic of Iran
(i) 0.0175” twist flex wire
(ii) Single stranded ribbon titanium
Composite:Transbond XT (Mandibular anterior teeth)
Failure rate
Detachments, time of debonding, side effects
2 years
19. Kartal et al. 2020 RCT n = 52
(13 F and 13 M in first group; 19 F and 27 M in second group)
Mean age
15.65 ± 2.17
18.42 ± 5.17
Private Practice, Turkey
(i) Memotain retainers (CAD-CAM technology) 0.014”
(ii) 0.0215” five-stranded retainers
Composite:Transbond XT
Success rate 6 months
20. Scribante 2011 RCT n = 34 patients (9 male, 25 female)
Mean age: 14.3 years
University of Pavia, Italy
(i) Multi-stranded Stainless steel; 0.0175 inch; mandible: all 6, n = 17
(ii) Polyethylene ribbon-reinforced resin composite; mandible: all 6; n = 15
Composite: Transbond XT (LC)
Bond failure 12 months
21. Kramer et al. 2020 RCT n = 104 (52 F and 52 M)
Mean age 17.1 years in VFR
Mean age 17.1 year in BR
Orthodontic Clinic in Gavle, Sweden.
(i) Cuspid to cuspid retainer
(ii) VFR
Wire: 0.8 Hard Remanium wire
Composite:Tetric Flw composite
Failure rate 18 months
22. Gokce 2019 Prospective study n = 100(61 F and 39 M)
Age: 16.5–18 years
Başkent University, Turkey
(i) 0.0215 “MSW direct technique
0.0125 MSW indirect
(ii) 0.0175 “MSW direct
0.0175 “MSW indirect
Removable essix
Transbond XT primer, 3M Unitek
Failure rate 6 months
23. Pop et al. 2018 Prospective study n = 53
Age:
11–53 years
Private clinic, Romania
(i) 0.0175 inch Round fixed retainers
(ii) 0.010–0.022-inch Flat wire retainers
Success rate 6 months
24. Sobouti et al. 2016 RCT n = 150
Mean age 18 ± 3.6 years
23 M and 24 F in FRC splint
17 M and 24 F in FSW
20 M and 25 F in TW
Mazandaran University of Medical Sciences, Iran
(i) 0.0175-inch FSW
(ii) FRC splint
(iii) Twisted 2—0.009-inch dead soft wire
Composite: Two layers of light-curable primer (Ormco, Orange, CA, USA)
Failure rate, detachment, breakage, or distortion 2 years
25. Stormann 2002 RCT n = 103
Age: 22.4 ± 9.7 years
Age: 13–17 years
Orthodontic practice, Germany
(i) Coaxial stainless steel 0.0215 inch; mandible: all 6; n = 36
(ii) Coaxial stainless steel 0.0195 inch; mandible: all 6; n = 30
(iii) Prefabricated; mandible: only canines; n = 32
Composite: Heliosit Orthodontic (LC) or Concise (CC)
Bond failure 2 years
26. Sfondrini 2014 RCT n = 87
(52 F and 35 M)
Age: 24 years (14–62 years)
University of Pavia, Italy
(i) Glass fibre reinforced; mandible: all 6; n = 40
(ii) Multi-stranded wire; 0.0175 inch; mandible: all 6; n = 47
Composite: Transbond XT (LC)
Detachments of retainers from the teeth 12 months
27. Nagani et al. 2020 RCT n = 56
Age
20.88 ± 3.45 FRC
22.15 ± 3.68 MSW
4 M and 22 F in FRC
4 M and 22 F in MSR
Dow University of Health Sciences, Pakistan
(i) Fiber reinforced retainers; n = 27
(ii) Multi-stranded retainers; n = 27
Composite: Flowable composite resin (3 M ESPE)
Retainer failure 12 months
28. Shim 2022 RCT n = 81
9 M,7 F, age median 16.5 in CAD/CAM
4 M, 12 F, median age 15.8 in Lab
5 M, 9 F, age median 15.2 in traditional group
Saint Louis University, Missouri
(i) CAD/CAM; n = 16
(ii) Lab; n = 16
(iii) Traditional; n = 14
Stability, failure of retainer 6 months
29. Wegrodzka et al. 2021 RCT N = 133 patients
Median age, 24.6 years; 25th percentile, 17.2 years; 75th percentile, 32.4 years; minimum, 15.1 years; maximum, 49.8 years
Private practice, Poland
0.0215-inch stainless-steel three-strand RT wire retainer (Ortho Organizers, Lindenberg, Germany)
0.0265-inch 3 0.0106-inch eight-strand Bond-a-Braid wire retainer (Reliance Orthodontic Products, Itasca, Ill)
Retainer failure, periodontal index, bleeding on probing, plaque index, gingival index, and probing depth. 2 years
30. Cornelis et al. 2022 RCT N = 64 participants
University of Geneva, Switzerland
Indirect bonding 26
Direct bonding 26
0.0215-inch multi-stranded stainless steel wire
Transbond LR Light Cure Adhesive (3M, Monrovia, California) composite.
Survival rate, the inter-canine and inter-premolar distances, and the observation of unexpected posttreatment changes 5 years
31. Gera et al. 2022 RCT N = 181 patients
98 in Centre 1, 83 in Centre 2
Aarhus University, Denmark University of Oslo, Norway.
CAD/CAM group (n = 90)
Conventional group (n = 91)
Stability, retainer failures and patient satisfaction. 6 months
32. Jowett et al. 2022 Multicentre RCT N = 68 patients
Leeds Dental Institute, St Luke’s Hospital, and Beverley Orthodontic Centre; UK
Upper and lower Memotain® bonded retainers (n = 34)
Upper and lower Ortho-FlexTechTM bonded retainers (n = 34)
Separate etch and bond along-side Transbond LR (3M Unitek, Monrovia, CA, USA) resin-based composite:
Stability of the inter-canine width and alignment of the labial segments, failure rate, patient satisfaction, and cost-effectiveness. 6 months
33. Danz et al. 2022 Prospective cohort study N = 200 participants
Median age 14.7
(Range 11.1–57.0)
University of Bern, Switzerland.
0215 inches MW with separate curing of resin and composite (n = 200)
016 inches 022 inches SS wire with simultaneous curing of resin and composite (SS1C) (n = 200)
016 022 inches SS wire with separate curing of resin and composite (SS2C) (n = 200)
Retention success, emergency, detachment, and retainer failure. 1 year
34. Cokakoglu et al. 2023 RCT N = 100 patients
70 females and 30 males
Pamukkale University, Turkey
Group 1, direct bonding (DB) with two-step adhesive (n =25)
Group 2, DB with one-step adhesive (n = 25)
Group 3, indirect bonding (IDB) with two-step adhesive (n = 25)
Group 4, IDB with one-step adhesive (n = 25)
The fixed retainer, a 0.0215-inch, five-strand stainless steel wire (Pentaflex; GC Orthodontics America Inc, Alsip, Ill)
Bonded with the direct or indirect method using either the primer integrated one-step (GC Ortho Connect Flow; GC Corp, Tokyo, Japan) or two-step (conventional) retainer adhesive (Transbond LR; 3M Unitek, Monrovia, California)
Plaque index, gingival index, and calculus index, failure rate. 12 months