Table 2.
Summary of the clinical evolution of different common markers in crohn's disease (CD) and ulcerative colitis (UC) at diagnosis, 3 months and 6 months.
| Clinical group | Timeline | PCDAI/PUCAI mean (IQR) | FC (mg/kg) | FC stratified (%) | EIM (ESR and/or CRP) (%) | ||
|---|---|---|---|---|---|---|---|
| FC1 | FC2 | FC3 | |||||
| CD | Diagnosis (n = 13) | 25 (10–47.5) | 2,166 (159–6,000) | 0% (n = 0) | 0% (n = 0) | 100% (n = 13) | 83% |
| 3 m (n = 12) | 0 (0–0) | 281 (50–2,880) | 50% (n = 6) | 17% (n = 2) | 33% (n = 4) | 0% | |
| 6 m (n = 11) | 0 (0–0) | 93 (6–1,973) | 64% (n = 7) | 0% (n = 0) | 36% (n = 4) | 0% | |
| UC | Diagnosis (n = 11) | 30 (10–80) | 3,381 (526–6,000) | 0% (n = 0) | 0% (n = 0) | 100% (n = 11) | 18% |
| 3 m (n = 10) | 0.5 (0–5) | 33 (7–1,042) | 90% (n = 9) | 0% (n = 0) | 10% (n = 1) | 0% | |
| 6 m (n = 7) | 0.5 (0–5) | 9 (0–380) | 90% (n = 6) | 0% | 10% (n = 1) | 3.3% | |
IQR, Interquartile range; PCDAI, Pediatric Crohn's Disease Activity Index; PUCAI, Pediatric Ulcerative Colitis Activity Index; FC, Fecal calprotectin; ESR, erythrocytic sedimentation rate; CRP, C-reactive protein; EIM, elevation of inflammatory markers.