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Higher susceptibility of hyperglycemic mice to K. pneumoniae infection. Mice were infected with ~100 CFU K. pneumoniae by tracheal instillation. (A) Survival curve of control and hyperglycemic (HG) mice demonstrating increased mortality of HG mice compared to controls. (B) Lung bacterial load was significantly higher in HG mice following 48 h of infection (n = 9). All experiments were repeated at least three times. Statistical differences were analyzed by Student’s t-test, *p < 0.05.
