Table 2.
Clinical and laboratory profile of all subjects
| Normal values | Non-AC group | AC group | P values | |
|---|---|---|---|---|
| No of subjects | 9 | 40 | ||
| Systolic pressure | < 120 mmHg | 126.89 ± 8.7 | 128.60 ± 3.49 | 0.36 |
| Diastolic pressure | < 80 mmHg | 76.73 ± 3.43 | 69.28 ± 1.94 | 0.04 |
| Body temperature | 36.1–37.2 °C | 36.97 ± 0.20 | 36.87 ± 0.11 | 0.34 |
| White blood cells | 3,300–8,600/µL | 8.05 ± 1.53 | 10.25 ± 0.80 | 0.08 |
| Blood platelets | 13.8–30.9 × 104 (µL) | 230.80 ± 31.88 | 178.60 ± 12.74 | 0.07 |
| Blood hemoglobin | 11.6–16.5 g/dL | 12.43 ± 0.61 | 11.68 ± 0.34 | 0.22 |
| Blood total protein | 6.5–8.0 g/dL | 6.45 ± 0.29 | 6.45 ± 0.11 | 0.45 |
| Blood albumin | 4.0–5.2 g/dL | 3.37 ± 0.23 | 3.09 ± 0.11 | 0.07 |
| Blood total bilirubin | 0.2–1.2 mg/dL | 3.17 ± 0.88 | 3.40 ± 0.40 | 0.33 |
| Blood direct bilirubin | 0–0.3 mg/dL | 2.12 ± 0.74 | 2.15 ± 0.42 | 0.49 |
| Serum aspartate aminotransferase | ≤ 30 U/L | 176.20 ± 55.71 | 204.30 ± 36.52 | 0.46 |
| Serum alanine transaminase | ≤ 30 U/L | 191.1 ± 53.2 | 155.20 ± 22.30 | 0.28 |
| Serum γ-glutamyl transpeptidase | ≤ 50 U/L | 391.0 ± 138.2 | 382.8 ± 51.02 | 0.40 |
| Serum alkaline phosphatase | 38–113 U/L | 272.70 ± 39.60 | 353.7 ± 46.57 | 0.44 |
| Serum amylase | 43–116 U/L | 97.63 ± 29.56 | 82.75 ± 11.69 | 0.45 |
| Serum Na | 135–147 mmol/L | 138.20 ± 1.61 | 137.5 ± 0.66 | 0.28 |
| Serum K | 3.3–4.8 mmol/L | 4.04 ± 0.22 | 4.02 ± 0.09 | 0.31 |
| Serum Cl | 98–108 mmol/L | 100.7 ± 2.42 | 100.1 ± 2.42 | 0.31 |
| Serum procalcitonin | < 0.05 ng/mL | 1.56 ± 1.20 | 5.66 ± 2.03 | 0.07 |
| Serum C-reactive protein | ≤ 0.3 mg/dL | 4.01 ± 1.77 | 9.97 ± 1.67 | 0.02 |
| Blood urea nitrogen | 7–24 mg/dL | 18.10 ± 2.81 | 26.12 ± 3.56 | 0.37 |
| Serum creatinine | ≤ 0.70 mg/dL | 1.40 ± 0.69 | 1.49 ± 0.25 | 0.04 |
| Activated partial thromboplastin time | 24–39 s | 34.84 ± 4.43 | 35.82 ± 1.43 | 0.16 |
| Prothrombin time (sec) | 9–13 s | 100.4 ± 11.81 | 80.92 ± 4.32 | 0.03 |
| Plasma fibrin-degradation products | < 5 µg/mL | 5.35 ± 1.24 | 15.77 ± 3.09 | 0.04 |
| Peripheral oxygen saturation | 95–100% | 97.44 ± 0.37 | 96.73 ± 0.40 | 0.15 |
| Plasma IL-6 | < 17.4 pg/mL | 178.20 ± 21.30 | 3088.0 ± 1294 | 0.02 |
| Plasma TNFα | 0–2.2 pg/mL | 288.1 ± 12.9 | 551.4 ± 109.6 | 0.48 |
| Plasma FasL | 0.2–1.5 pg/mL | 62.13 ± 6.36 | 70.16 ± 5.94 | 0.20 |
| Bile IL-6 | < 10 pg/mL | 259.70 ± 95.02 | 819.90 ± 299.60 | 0.05 |
| Bile TNFα (pg/mL) | < 5 pg/mL | 374.70 ± 72.79 | 671.60 ± 122.80 | 0.13 |
| Bile FasL (pg/mL) | 0.5–2.5 pg/mL | 115.50 ± 9.99 | 132.40 ± 18.25 | 0.17 |
Data are expressed as the mean ± standard error of the mean
TNF-α, tumor necrosis factor-α; IL-6, interleukin-6; AC, acute cholangitis