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. 2023 Nov 30;15:59. doi: 10.1186/s13099-023-00587-4

Table 3.

Clinical profile and laboratory data by disease severity

Non-AC Non-severe AC Severe AC
No of subjects 9 30 10
Age (years-old ± SEM) 72.89 ± 6.03 80.70 ± 2.06 78.50 ± 3.02
Systolic pressure (mmHg) 126.80 ± 8.07 131.03 ± 3.25 120.60 ± 9.99
Diastolic pressure (mmHg) 75.80 ± 3.65 70.97 ± 2.06 64.20 ± 4.53
White blood cells (103/µL) 8.05 ± 1.53 9.22 ± 0.73 13.33 ± 2.13*†
Blood platelets (104/µL) 230.80 ± 31.88 200.00 ± 13.64 114.20 ± 20.09*†
Blood hemoglobin (g/dL) 12.43 ± 0.61 11.76 ± 0.40 11.44 ± 0.67
Blood total protein (g/dL) 6.45 ± 0.29 6.50 ± 0.13 6.31 ± 0.17
Blood albumin (g/dL) 3.37 ± 0.23 3.11 ± 0.13 3.04 ± 0.18
Blood total bilirubin (mg/dL) 3.17 ± 0.88 3.03 ± 0.43 4.48 ± 0.94
Blood direct bilirubin (mg/dL) 2.12 ± 0.74 1.66 ± 0.37 4.22 ± 1.30
Serum aspartate aminotransferase (U/L) 176.20 ± 55.71 210.60 ± 43.55 185.10 ± 68.73
Serum alanine transaminase (U/L) 191.10 ± 53.20 146.90 ± 23.43 180.20 ± 56.77
Serum γglutamyl transpeptidase (U/L) 391.00 ± 138.20 379.90 ± 62.07 391.20 ± 89.97
Serum alkaline phosphatase (U/L) 272.70 ± 39.60 334.20 ± 53.91 412.10 ± 94.80
Serum amylase (U/L) 97.63 ± 29.56 76.87 ± 13.11 100.4 ± 25.67
Serum Na (mmol/L) 138.20 ± 1.61 138.00 ± 0.67 135.90 ± 166
Serum K (mmol/L) 4.04 ± 0.22 4.01 ± 0.08 4.06 ± 0.28
Serum Cl (mmol/L) 100.70 ± 2.42 100.30 ± 3.18 99.70 ± 1.86
Serum procalcitonin 1.56 ± 1.20 2.63 ± 1.22 17.34 ± 7.53*†
Serum C-reactive protein (mg/dL) 4.01 ± 1.77 6.75 ± 1.36 20.73 ± 4.07*†
Blood urea nitrogen (mg/dL) 18.10 ± 2.81 16.55 ± 1.22 54.85 ± 9.13*†
Serum creatinine (mg/dL) 1.40 ± 0.69 0.86 ± 0.04 3.38 ± 0.78*†
Activated partial thromboplastin time (sec) 34.84 ± 4.43 36.02 ± 1.77 35.17 ± 2.07
Prothrombin time (sec) 100.40 ± 11.81 81.86 ± 5.20 77.89 ± 7.62
Plasma fibrin-degradation products 5.35 ± 1.24 12.44 ± 3.08 26.99 ± 7.77*†
Peripheral oxygen saturation (%) 97.44 ± 0.37 96.63 ± 0.51 97.00 ± 0.47

Data are expressed as the mean ± standard error of the mean

AC, acute cholangitis; SEM, standard error of the means; TNF-α, tumor necrosis factor-α; IL-6, interleukin-6

*p < 0.5 vs non-AC; p < 0.01 vs non-severe AC