Table 3.
Clinical profile and laboratory data by disease severity
| Non-AC | Non-severe AC | Severe AC | |
|---|---|---|---|
| No of subjects | 9 | 30 | 10 |
| Age (years-old ± SEM) | 72.89 ± 6.03 | 80.70 ± 2.06 | 78.50 ± 3.02 |
| Systolic pressure (mmHg) | 126.80 ± 8.07 | 131.03 ± 3.25 | 120.60 ± 9.99 |
| Diastolic pressure (mmHg) | 75.80 ± 3.65 | 70.97 ± 2.06 | 64.20 ± 4.53 |
| White blood cells (103/µL) | 8.05 ± 1.53 | 9.22 ± 0.73 | 13.33 ± 2.13*† |
| Blood platelets (104/µL) | 230.80 ± 31.88 | 200.00 ± 13.64 | 114.20 ± 20.09*† |
| Blood hemoglobin (g/dL) | 12.43 ± 0.61 | 11.76 ± 0.40 | 11.44 ± 0.67 |
| Blood total protein (g/dL) | 6.45 ± 0.29 | 6.50 ± 0.13 | 6.31 ± 0.17 |
| Blood albumin (g/dL) | 3.37 ± 0.23 | 3.11 ± 0.13 | 3.04 ± 0.18 |
| Blood total bilirubin (mg/dL) | 3.17 ± 0.88 | 3.03 ± 0.43 | 4.48 ± 0.94 |
| Blood direct bilirubin (mg/dL) | 2.12 ± 0.74 | 1.66 ± 0.37 | 4.22 ± 1.30 |
| Serum aspartate aminotransferase (U/L) | 176.20 ± 55.71 | 210.60 ± 43.55 | 185.10 ± 68.73 |
| Serum alanine transaminase (U/L) | 191.10 ± 53.20 | 146.90 ± 23.43 | 180.20 ± 56.77 |
| Serum γglutamyl transpeptidase (U/L) | 391.00 ± 138.20 | 379.90 ± 62.07 | 391.20 ± 89.97 |
| Serum alkaline phosphatase (U/L) | 272.70 ± 39.60 | 334.20 ± 53.91 | 412.10 ± 94.80 |
| Serum amylase (U/L) | 97.63 ± 29.56 | 76.87 ± 13.11 | 100.4 ± 25.67 |
| Serum Na (mmol/L) | 138.20 ± 1.61 | 138.00 ± 0.67 | 135.90 ± 166 |
| Serum K (mmol/L) | 4.04 ± 0.22 | 4.01 ± 0.08 | 4.06 ± 0.28 |
| Serum Cl (mmol/L) | 100.70 ± 2.42 | 100.30 ± 3.18 | 99.70 ± 1.86 |
| Serum procalcitonin | 1.56 ± 1.20 | 2.63 ± 1.22 | 17.34 ± 7.53*† |
| Serum C-reactive protein (mg/dL) | 4.01 ± 1.77 | 6.75 ± 1.36 | 20.73 ± 4.07*† |
| Blood urea nitrogen (mg/dL) | 18.10 ± 2.81 | 16.55 ± 1.22 | 54.85 ± 9.13*† |
| Serum creatinine (mg/dL) | 1.40 ± 0.69 | 0.86 ± 0.04 | 3.38 ± 0.78*† |
| Activated partial thromboplastin time (sec) | 34.84 ± 4.43 | 36.02 ± 1.77 | 35.17 ± 2.07 |
| Prothrombin time (sec) | 100.40 ± 11.81 | 81.86 ± 5.20 | 77.89 ± 7.62 |
| Plasma fibrin-degradation products | 5.35 ± 1.24 | 12.44 ± 3.08 | 26.99 ± 7.77*† |
| Peripheral oxygen saturation (%) | 97.44 ± 0.37 | 96.63 ± 0.51 | 97.00 ± 0.47 |
Data are expressed as the mean ± standard error of the mean
AC, acute cholangitis; SEM, standard error of the means; TNF-α, tumor necrosis factor-α; IL-6, interleukin-6
*p < 0.5 vs non-AC; †p < 0.01 vs non-severe AC