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. 2023 Nov 30;42:328. doi: 10.1186/s13046-023-02886-9

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — EFEMP1 expression in primary tumours correlates with poor prognosis in OS patients. A Representative images of EFEMP1 staining and H&E in biopsy samples of high-grade OS patients at x100 magnification (Scale bar: 50 μm). B, C Kaplan-Meier analysis of overall survival in chondroblastic, fibroblastic and osteoblastic OS patient samples (n = 73 patients) and with metastatic disease (n = 37 patients). Scan cut-off was used to group samples into high (blue) and low (red) EFEMP1 expressions. p-values were determined by a log-rank test