Table 3.

Duration of treatment according to extent-of-TB-disease phenotype at screening/baseline

Any lung cavity	Screening sputum AFB smear grade
	Negative or scanty	1 +	2 +	3 +
Cavity absent	24 weeks of treatmenta	24 weeks of treatmenta	39 weeks of treatment	39 weeks of treatment
Cavity present	24 weeks of treatmenta	39 weeks of treatment	39 weeks of treatment	39 weeks of treatment

Abbreviation: AFB acid-fast bacilli. Screening sputum AFB smear grade is assigned based on the highest smear grade from a screening (or baseline) sputum sample (N = 3). Cavitary disease is defined as the presence of at least one lung cavity on the baseline chest radiograph

^aThese participants might have treatment extended to 39 weeks based on treatment response, defined by sputum culture results assessed at week 8 or between week 8 and week 24