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. 2023 Nov 16;8(47):45163. doi: 10.1021/acsomega.3c08464

Figure 5.

Figure 5

U937 cells activated with LPS (100 ng/mL) plus TNFα (100 ng/mL) for 24 h, alone or in combination with 3 or 7 at 0.1, 1, 10, 100, and 1000 nM. Dexamethasone (Dex) was used at 5 μM. Quantitative real-time PCR analysis of expression of proinflammatory genes IL-1β (A and E), TNFα (B and F), IL-6 (C and G) and M1 marker CD11c (D and H). These data are normalized to TBP mRNA expression. Data are derived from five replicates. Results represent mean ± SEM # p < 0.05 vs NT group and *p < 0.05 vs LPS plus TNFα group. N.D. means not determined. Analysis of variance (ANOVA) was used for statistical comparisons.