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. 2023 Nov 14;8(47):44424–44436. doi: 10.1021/acsomega.3c04134

Table 1. Comparison between the Significant Features of Ultraviolet and near-Infrared Light Irradiations in Photodynamic and Photothermal Therapies.

  UV stimulation NIR stimulation
wavelength range (nm) 200–400 650–900
energy more energetic less energetic
photochemical reactions more effective less effective
penetration poor body tissue penetration (<1 mm) deep body tissue penetration (1–4 mm)
effectiveness against deep tumors not effective against deep tumors effective against deep tumors
effective against superficial tumors
applicability in PTT and PDT can be transformed into heat (for PTT) or reactive oxygen species (for PDT) can be transformed into heat (for PTT) or reactive oxygen species (for PDT)
safety hazardous to healthy tissues (could be absorbed by lipids and hemoglobin) safer to healthy tissues