Table 1. Summary of Reviewed Methods.

model name	representation	database	main idea
IterRefLSTM14	graph	SIDER, Tox21, MUV	refined LSTM iteratively/one-shot learning
Torres’s model18	SMILES with one-hot	Tox21	SNN/one-shot learning
SiameseCHEM19	task-specific fingerprint	ChEMBL, ExCAPE-DB	SNN/N-shot learning
Vella’s model22	graph, ECFP	Tox21, MUV, GPCR	prototypical network/few-shot learning