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. 2023 Oct 30;97(11):e00771-23. doi: 10.1128/jvi.00771-23

Fig 3.

Fig 3

RSV preF-specific IgG, IgA, and IgM trajectories. RSV preF-specific (a) IgG1, (b) IgG2, (c) IgG3, (d) IgG4, (e) IgA1, (f) IgA2, and (g) IgM were measured in serum samples collected at day 15 for participants receiving the Ad26.RSV.preF/RSV preF protein combination vaccine (n = 15), Ad26.RSV.preF alone (n = 8), RSV preF protein alone (n = 8), or placebo (n = 8). Responses at day 15 were baseline corrected (day 0, prior to vaccination), and only positive values are shown. Horizontal lines denote geometric mean values in each group. Statistical comparisons were performed by non-parametric analysis of variance (Kruskal-Wallis) with Benjamini-Hochberg correction for multiple comparisons. *P ≤ 0.05; **P ≤ 0.01; ***P < 0.001. Ad26, adenovector type 26; Ig, immunoglobulin; MFI, median fluorescence intensity; preF, pre-fusion conformation-stabilized RSV F protein; RSV, respiratory syncytial virus.