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. 2023 Oct 30;97(11):e00771-23. doi: 10.1128/jvi.00771-23

Fig 4.

Fig 4

RSV preF-specific Fc receptor binding induced by Ad26.RSV.preF, RSV preF protein, and the Ad26.RSV.preF/RSV preF protein combination vaccine. RSV preF-specific (a) FcαR, (b) FcγR2a, (c) FcγR2b, (d) FcγR3a, and (e) FcγR3b binding were measured in serum samples collected at day 15 for participants receiving the Ad26.RSV.preF/RSV preF protein combination vaccine (n = 15), Ad26.RSV.preF alone (n = 8), RSV preF protein alone (n = 8), or placebo (n = 8). Horizontal lines denote geometric mean values in each group. Responses at day 15 were baseline corrected (day 0, prior to vaccination), and only positive values are shown. Statistical comparisons were performed by non-parametric analysis of variance (Kruskal-Wallis) with Benjamini-Hochberg correction for multiple comparisons. *P ≤ 0.05; **P ≤ 0.01; ***P < 0.001. Ad26, adenovector type 26; FcαR, Fcα receptor; FcγR, Fcγ receptor; MFI, median fluorescence intensity; preF, pre-fusion conformation-stabilized RSV F protein; RSV, respiratory syncytial virus.